Studies on Alismatis Rhizoma. III. Stereostructures of New Protostane-Type Triterpenes, Alisols H, I, J-23-Acetate, K-23-Acetate, L-23-Acetate, M-23-Acetate, and N-23-Acetate, from the Dried Rhizome of Alisma orientale.

Alisol C 23-acetate from the rhizome of Alisma orientale

THE TITLE COMPOUND [SYSTEMATIC NAME: 11β-hydr-oxy-24,25-ep-oxy-3,16-oxo-protost-13 (17)-en-23-yl acetate], C(32)H(48)O(6), a protostane-type triterpenoid, was isolated from the Chinese herbal medicine alismatis rhizoma (the rhizome of Alisma orientalis Juzep). The mol-ecule contains four trans-fused rings, viz. three six-membered and one five-membered ring. Two of the six-membered rings have sl...

The zwitterion (23′E)-(23R,25S)-23-[1-(oxidoiminio)eth­yl]-5β-spiro­stan-3β-yl acetate

The title steroidal compound, C(31)H(49)NO(5), resulted from the selective oximation of (23R)-23-acetyl-sarsasapogenin acetate. One- and two-dimensional (1)H and (13)C NMR spectra, as well as IR data, are in agreement with the presence of a ketoxime group at C-23. However, recrystallization in slightly acidic media affords the title compound in the rare zwitterionic oxime form, as a consequence...

Protective effects of alisol B 23-acetate from edible botanical Rhizoma alismatis against carbon tetrachloride-induced hepatotoxicity in mice.

Carbon tetrachloride (CCl4)-induced hepatotoxicity is a common syndrome with simultaneous severe hepatocyte death and acute cholestasis. The purpose of the present study is to investigate the hepatoprotective effect of alisol B 23-acetate (AB23A), a natural triterpenoid from edible botanical Rhizoma alismatis, on acute hepatotoxicity induced by CCl4 in mice, and further to elucidate the involve...

Cyproterone acetate-ethinyl estradiol use in a 23-year-old woman with stroke.

Diuretic Activity of Compatible Triterpene Components of Alismatis rhizoma.

Alismatis rhizoma (AR), the dried rhizoma of Alisma orientale Juzepzuk (Alismataceae), is a traditional Chinese medicine. AR is an important part of many prescriptions and is commonly used as a diuretic agent in Asia. This study aimed to evaluate the diuretic effects of total triterpene extract (TTE) and triterpene component compatibility (TCC, the mixture of alisol B 23-acetate, alisol B, alis...